Table 3.
Summary of methodological quality of the included studies on the basis of the review authors' judgments on the items in the QUADAS checklist for each study.
| QUADAS | Number | |||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | |
| Representative patient spectrum? | No | No | No | No | No | No |
| Selection criteria | Unclear | Yes | Unclear | Unclear | Yes | Yes |
| Acceptable reference standard? | Yes | Yes | Yes | Yes | Yes | Yes |
| Acceptable delay between tests? | Yes | Yes | Yes | Yes | Yes | Yes |
| Partial verification avoided? | Yes | Yes | Yes | Yes | Yes | Yes |
| Differential verification avoided? | Yes | Yes | Yes | Yes | Yes | Yes |
| Incorporation avoided? | Yes | Yes | Yes | Yes | Yes | Yes |
| Index test execution | Yes | Yes | Yes | Yes | Yes | Yes |
| Reference standard execution | Yes | Yes | Yes | Yes | Yes | Yes |
| Reference standard results blinded? | Yes | Yes | Yes | Yes | Yes | Yes |
| Index test results blinded? | Yes | Yes | Yes | Yes | Yes | Yes |
| Relevant clinical information? | Yes | Yes | Yes | Yes | Yes | Yes |
| Quality of the studies | A | A | A | A | A | A |