TABLE 3.
Integronb | Cassette | % of isolates containing integron cassette |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bwindi |
Kibale |
All (n = 499) | ||||||||||||
HU (n = 48) | CA (n = 3) | GT (n = 27) | GO (n = 37) | HU (n = 276) | DO (n = 0) | CA (n = 8) | GT (n = 40) | BW (n = 11) | RC (n = 11) | RT (n = 25) | CZ (n = 13) | |||
A | dfrA17 | 33.3 | 66.7 | 14.8 | 0.0 | 24.3 | 0.0 | 12.5 | 10.0 | 0.0 | 0.0 | 0.0 | 0.0 | 18.8 |
B | dfrA1 aadA1 | 4.2 | 0.0 | 7.4 | 2.7 | 3.6 | 0.0 | 0.0 | 10.0 | 9.1 | 0.0 | 16.0 | 0.0 | 4.8 |
C | dfrA5 | 8.4 | 0.0 | 0.0 | 0.0 | 2.2 | 0.0 | 0.0 | 5.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.4 |
D | dfrA17 aadA5 | 8.4 | 0.0 | 0.0 | 0.0 | 2.9 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.4 |
E | dfrA15 aadA1 | 2.1 | 0.0 | 0.0 | 0.0 | 2.5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.6 |
F | aadA1 | 6.3 | 0.0 | 0.0 | 0.0 | 1.1 | 0.0 | 0.0 | 2.5 | 0.0 | 0.0 | 0.0 | 0.0 | 1.4 |
G | blaOXA-1 aadA2 | 0.0 | 0.0 | 0.0 | 0.0 | 2.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.2 |
H | dfrA1 catB3 aacA4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.7 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.4 |
I | dfrA12 aadA2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.5 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 |
Allc | 62.7 | 66.7 | 22.2 | 2.7 | 39.5 | 0.0 | 12.5 | 30.0 | 9.1 | 0.0 | 16.0 | 0.0 | 33.3 |
Values in parentheses indicate numbers of phenotypically resistant (multiple and single resistance) E. coli isolates tested for class 1 integrons using PCR. Values in the table indicate percentages of such isolates containing the specified integron cassette. HU, human; CA, cattle; GT, goat/sheep; GO, mountain gorilla; DO, dog; BW, black-and-white colobus; RC, red colobus; RT, red-tailed guenon; CZ, chimpanzee. Complete integron cassette sequences are available in GenBank (accession numbers MH560801 to MH560966).
Nine E. coli isolates, all from humans, contained two class 1 integrons, i.e., four isolates containing integrons C and F, two isolates containing integrons A and B, two isolates containing integrons A and D, and one isolate containing integrons A and F.
Frequency of all class 1 integrons combined.