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. Author manuscript; available in PMC: 2018 Oct 18.
Published in final edited form as: Eur J Pharmacol. 2008 Feb 5;584(2-3):213–221. doi: 10.1016/j.ejphar.2008.01.036

Fig. 2.

Fig. 2.

Chemical names and structures of various inhibitors used for AKR1B10 wild-type and mutant proteins inhibition studies. Ciprofibrate for 2-[p-(2,2dichlorocyclopropyl)-phenoxy]-2-methylpropanoic acid, EBPC for ethyl-1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, fenofibrate for the isopropyl ester of 2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropanoic acid, fenofibric acid for 2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropanoic acid, gemfibrozil for 2,2dimethyl-5-[2,5-dimethylphenoxy]-pentanoic acid, sorbinil for 2,4-dihydro-6-fluorospiro[4H-1-benzopyran-4,4′-imidazolidine-]-2′,5′-dione, Wy 14,643 for 4-chloro6-(2,3-xylidino)-2-pyrimidinylthioacetic acid and zopolrestat for 3,4-dihydro-4-oxo-3-{[5-(trifluoromethyl)-2-benzothiazolyl]methyl}−1-phthalazineacetic acid.