Table 1.

Baseline mean values of metabolites that were significantly different between MDD vs healthy controls (Student t test, p value < 0.05)

Metabolites	Control (μM)	MDD (μM)
Citrulline	23.80 ± 7.22	19.25 ± 5.17
Serine	77.81 ± 21.86	62.93 ± 14.62
Threonine	96.70 ± 27.43	82.47 ± 22.54
Tryptophan	43.24 ± 10.74	37.32 ± 10.79
Alpha-amino adipidic acid	0.75 ± 0.59	0.68 ± 0.56
Kynurenine	1.32 ± 0.43	1.31 ± 0.36
Serotonin	0.17 ± 0.16	0.19 ± 0.19
SM C26:1	0.21 ± 0.08	0.16 ± 0.06
Kynurenine/Trp	0.03 ± 0.01	0.035 ± 0.008