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. 2018 Oct 11;9:471. doi: 10.3389/fpsyt.2018.00471

Figure 2.

Figure 2

CUMS induced spatial learning and memory impairment, while minocycline treatment reversed the alteration in both adolescent and adult rats. (A) Number of crossings of the platform in the MWM test; (B) Target quadrant entries percentage in the MWM test. Results are expressed as the mean ± SEM (n = 10 in each group). # and ## indicate p < 0.05 and p < 0.01 vs. C group, respectively; * and ** indicate p < 0.05 and p < 0.01 vs. S group, respectively. AdoC, adolescent control group; AdoS, adolescent CUMS group; AdoS+M, adolescent CUMS and minocycline group; AduC, adult control group; AduS, adult CUMS group; AduS+M, adult CUMS and minocycline group.