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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: Cancer Res. 2018 Aug 2;78(20):5741–5753. doi: 10.1158/0008-5472.CAN-18-0655

Figure 4. miR-24-3p has a pro-tumorigenic role in vivo, in MPM.

Figure 4

REN transduced with miR-empty and miR-Zip24 vectors were injected i.p. in NOD-SCID mice. Experimental groups: mice with miR-empty n=12; mice with miR-Zip24 n=12. A) Mice overall survival. KM indicates that knockdown of miR-24-3p increases mice survival. B) Representative images of control and knockdown mice: depletion of miR-24-3p causes a reduction of metastasis and less bleeding. C) miR-24-3p knockdown significantly reduces body, diaphragm and tumor mass weight. Data are represented as mean ± SD. Statistical p-values are indicated (*p ≤ 0.05).