Table 1. Study population baseline characteristics according to incident major osteoporotic fracture (MOF) or incident hip fracture (HF).
| VARIABLE | Overall | No MOF | Incident MOF | p-value | No HF | Incident HF | p-value |
|---|---|---|---|---|---|---|---|
| N = 44,543 | N = 40,597 | N = 3946 | N = 43,381 | N = 1162 | |||
| Age (years) | 63.9 ± 11.0 | 63.4 ± 10.8 | 68.6 ± 11.0 | <0.001 | 63.6 ± 10.9 | 73.3 ± 9.5 | <0.001 |
| Sex (men) | 4484 (10.1) | 4166 (10.3) | 318 (8.1) | <0.001 | 4391 (10.1) | 93 (8.0) | 0.018 |
| BMI (kg/m2) | 26.4 ± 4.4 | 26.4 ± 4.4 | 25.8 ± 4.4 | <0.001 | 26.4 ± 4.4 | 25.1 ± 4.2 | <0.001 |
| Prior fracture | 6658 (14.9) | 5693 (14.0) | 965 (24.5) | <0.001 | 6359 (14.7) | 299 (25.7) | <0.001 |
| Femoral neck T-score | -1.4 ± 1.0 | -1.3 ± 1.0 | -1.9 ± 0.9 | <0.001 | -1.3 ± 1 | -2.2 ± 0.8 | <0.001 |
| FRAX 10-year MOF fracture risk (%) a | 9.5 ± 6.8 | 9.2 ± 6.5 | 13.3 ± 8.4 | <0.001 | 9.4 ± 6.7 | 16.5 ± 8.7 | <0.001 |
| FRAX 10-year HF risk (%) a | 2.2 ± 3.7 | 2.0 ± 3.5 | 4.0 ± 4.8 | <0.001 | 2.1 ± 3.6 | 5.7 ± 5.2 | <0.001 |
| Lumbar spine TBS | 1.262 ± 0.123 | 1.267 ± 0.121 | 1.211 ± 0.125 | <0.001 | 1.264 ± 0.122 | 1.188 ± 0.121 | <0.001 |
| Diabetes | 4136 (9.3) | 3750 (9.2) | 386 (9.8) | 0.260 | 3997 (9.2) | 139 (12.0) | 0.001 |
a
FRAX score computed with femoral neck BMD but without TBS. Data are mean ± SD or N (percent). BMI, body mass index. TBS, trabecular bone score