Table 3. Calibration ratios for observed versus predicted 10-year major osteoporotic fracture (MOF) probability percent or hip fracture (HF) probability percent using unadjusted FRAX (referent) and four adjustments applied to those with diabetes.

	No diabetes			Diabetes, any duration
	N = 40,407			N = 4136
	Predicted	Observed	Calibration ratio	Predicted	Observed	Calibration ratio
MOF prediction
FRAX MOF unadjusted	9.5	9.5	1.00 (0.97-1.04)	10.3	11.9	1.15 (1.03-1.28)
With RA adjustment				13.1	11.9	0.91 (0.81-1.01)
With TBS adjustment				11.7	11.9	1.02 (0.91-1.12)
With T-score lowered 0.5 SD				12.4	11.9	0.96 (0.86-1.06)
With age raised 10 years				12.9	11.9	0.93 (0.83-1.03)
HF prediction
FRAX HF unadjusted	2.2	2.5	1.17 (1.08-1.25)	2.5	4.5	1.85 (1.51-2.20)
With RA adjustment				3.4	4.5	1.35 (1.10-1.60)
With TBS adjustment				2.8	4.5	1.63 (1.33-1.93)
With T-score lowered 0.5 SD				3.7	4.5	1.22 (0.99-1.44)
With age raised 10 years				3.7	4.5	1.22 (0.99-1.44)

Boldface indicates p-value <0.05. RA, rheumatoid arthritis. TBS, trabecular bone score. 10-year fracture probability includes competing mortality.