FIG 5.

Effect of oral administration of P. gingivalis on serum metabolites. (A) PCA of serum metabolites from P. gingivalis- and sham-administered mice. (B) Serum amino acids that differed in abundance between the two groups. Alanine (Ala), glutamine (Gln), histidine (His), tyrosine (Tyr), and phenylalanine (Phe) were significantly increased in the P. gingivalis-administered mice, and glutamate (Glu) was nonsignificantly increased. *, P < 0.05, Mann-Whitney U test. Pg, P. gingivalis-administered mice; Sham, sham-administered mice.