Table 5. Uni- and multivariate analysis of factors associated with 5-year disease-specific mortality.

	Univariate			Multivariate
	HR	95% CI	p value	HR	95% CI	p value
Supraclavicular node	5.59	2.08–15.01	<0.01**	4.57	1.20–17.39	0.026*
Distant metastasis	4.56	2.00–10.38	<0.01**	2.85	1.04–7.81	0.042*
Neck recurrence	7.99	3.31–19.27	<0.01**	4.21	1.37–12.91	0.012*
Alcohol	2.60	1.12–6.03	0.026*	2.24	0.71–7.03	0.168
Betel nut	2.41	1.08–5.36	0.032*	0.92	0.30–2.85	0.880
Smoking	3.41	1.17–9.95	0.025*	1.77	0.53–5.98	0.357
Nodal Stage
N1/N2a	reference				reference
N2b/N2c	2.40	0.54–10.74	0.251	2.26	0.32–15.98	0.416
N3	5.84	1.29–26.43	0.022*	3.84	0.55–26.90	0.175
Treatment
ND	0.22	0.03–1.79	0.155	0.30	0.03–3.27	0.321
ND + adjuvant therapy	0.33	0.13–0.86	0.024*	0.27	0.07–0.97	0.044*
RT alone		reference			reference
Combined therapy	0.23	0.06–0.82	0.023*	0.28	0.05–1.47	0.133

Cox regression.

*p<0.05,

**p<0.01