Skip to main content
. 2018 Oct 18;13(10):e0205971. doi: 10.1371/journal.pone.0205971

Table 2. Diagnostic measures for 1000 simulations in each null and predictive case.

Columns 4 and 5 show the bias and the MSE for the point estimate of the PITE. The sixth column shows the median width of the confidence intervals for the PITE, and the last columns the proportion of subjects in the identified subgroup when considering the using the limits of the confidence intervals and the point estimates. Since methods reduced and reduced-Scheffe have the same point estimate, bias and MSE are equal.

Case n Method Bias MSE Width Proportion of subjects in subgroup
% in B^l % in B^ % in B^u % in B
Null 40 ATE 0.01 0.38 1.48 1.6 53.8 96.0 0.0
40 full -0.01 1.65 6.35 2.0 48.5 97.5 0.0
40 Lasso -0.00 0.35 5.24 0.6 45.0 93.6 0.0
40 reduced 0.01 0.87 1.56 15.9 45.5 77.8 0.0
40 reduced-Scheffe 0.01 0.87 5.80 0.0 45.5 94.1 0.0
40 rLasso-1 0.00 0.86 3.37 1.4 46.9 94.0 0.0
40 rLasso-2 -0.01 0.78 2.49 1.6 45.3 93.5 0.0
100 ATE -0.00 0.21 0.84 2.1 49.3 97.5 0.0
100 full 0.02 0.76 2.90 2.2 50.7 97.8 0.0
100 Lasso 0.01 0.22 3.00 0.9 48.0 93.4 0.0
100 reduced 0.02 0.56 1.02 17.1 47.2 79.9 0.0
100 reduced-Scheffe 0.02 0.56 3.24 0.0 47.2 94.7 0.0
100 rLasso-1 0.01 0.54 2.20 1.9 48.1 94.9 0.0
100 rLasso-2 0.02 0.46 1.61 1.6 51.2 95.6 0.0
220 ATE 0.01 0.13 0.54 1.3 52.2 98.3 0.0
220 full 0.00 0.47 1.79 3.1 49.9 97.7 0.0
220 Lasso 0.00 0.16 2.15 1.2 47.2 92.9 0.0
220 reduced -0.01 0.38 0.73 14.2 47.2 78.0 0.0
220 reduced-Scheffe -0.01 0.38 2.21 0.0 47.2 93.8 0.0
220 rLasso-1 -0.01 0.37 1.48 2.7 49.5 94.7 0.0
220 rLasso-2 0.00 0.34 1.11 2.1 47.6 93.8 0.0
350 ATE -0.01 0.11 0.43 1.7 46.7 97.1 0.0
350 full 0.01 0.39 1.40 2.8 50.7 97.3 0.0
350 Lasso 0.00 0.13 1.60 1.3 46.3 93.9 0.0
350 reduced 0.00 0.31 0.56 16.0 46.4 79.5 0.0
350 reduced-Scheffe 0.00 0.31 1.65 0.0 46.4 95.7 0.0
350 rLasso-1 0.01 0.30 1.09 2.4 48.8 94.3 0.0
350 rLasso-2 0.00 0.28 0.86 2.3 48.2 93.8 0.0
Predictive 40 ATE 0.01 0.75 1.57 10.9 75.2 98.8 64.7
40 full -0.03 1.67 6.37 4.8 55.3 97.7 64.7
40 Lasso -0.19 0.62 6.15 2.2 54.1 96.3 64.7
40 reduced -0.10 0.97 1.85 24.7 54.7 81.7 64.7
40 reduced-Scheffe -0.10 0.97 6.72 0.0 54.7 97.6 64.7
40 rLasso-1 -0.10 0.97 4.02 3.4 54.8 96.2 64.7
40 rLasso-2 -0.14 0.90 3.02 3.9 53.8 94.0 64.7
100 ATE 0.00 0.68 0.88 18.9 86.2 100.0 62.3
100 full 0.02 0.76 2.90 13.3 61.1 95.6 62.3
100 Lasso -0.14 0.47 3.00 11.4 59.6 93.9 62.3
100 reduced -0.03 0.61 1.31 33.1 59.0 83.4 62.3
100 reduced-Scheffe -0.03 0.61 4.10 0.1 59.0 99.8 62.3
100 rLasso-1 -0.04 0.61 2.52 10.6 60.0 94.0 62.3
100 rLasso-2 -0.08 0.59 1.94 13.5 57.7 91.1 62.3
220 ATE 0.01 0.65 0.57 44.2 96.3 100.0 61.5
220 full -0.00 0.47 1.79 22.1 61.0 91.4 61.5
220 Lasso -0.14 0.34 1.97 16.5 58.6 89.9 61.5
220 reduced -0.02 0.41 0.99 39.2 60.7 81.7 61.5
220 reduced-Scheffe -0.02 0.41 2.96 2.3 60.7 99.6 61.5
220 rLasso-1 -0.04 0.42 1.70 19.3 59.0 89.5 61.5
220 rLasso-2 -0.07 0.43 1.36 24.6 60.0 85.6 61.5
350 ATE 0.01 0.63 0.45 57.5 97.8 100.0 63.5
350 full 0.01 0.39 1.40 27.5 63.4 90.9 63.5
350 Lasso -0.13 0.29 1.40 24.1 58.1 88.8 63.5
350 reduced -0.02 0.33 0.80 41.0 61.8 79.9 63.5
350 reduced-Scheffe -0.02 0.33 2.38 7.2 61.8 98.7 63.5
350 rLasso-1 -0.02 0.33 1.28 27.6 60.8 88.0 63.5
350 rLasso-2 -0.05 0.35 1.10 29.5 60.1 84.0 63.5