Table 4. HT and the Risk of CHD.

	All patient				Symptomatic menopausal cohort patient		Control cohort patient
	cHR (95% CI)§	P-value	aHR (95% CI)‡	P-value	aHR (95% CI)‡	P-value	aHR (95% CI)‡	P-value
CHD
Non-user	1(reference)		1(reference)		1(reference)		1(reference)
HT user※	1.409(1.305,1.52)	< .0001	1.076(0.985,1.176)	0.1031	1.082(0.986,1.187)	0.0953	1.306(0.998,1.71)	0.0517

^§Model was adjusted for HT.

^‡Model was adjusted for HT and all variables listed in Table 1.

^※HT was used as a time-dependent covariate for eliminating the effects of immortal time bias.

All analyses incorporated with regard to death as competing risks.

HT: hormone therapy