Men			Women
Variable	N (%)	TBS Least Square Mean (%95CLI)	P value for trend	N (%)	TBS Least Square Mean (%95CLI)	P value for trend	P value for Interaction
Age (years)	N= 369		0.19	N= 303		0.017*	0.15
50–54	50 (13.55%)	1.333 (1.291 – 1.376)
55–59	66 (17.89%)	1.314 (1.270 – 1.357)		83 (27.39%)	1.294 (1.264 – 1.325)
60–64	116 (31.44%)	1.294 (1.252 – 1.336)		102 (33.66%)	1.271 (1.242 – 1.301)
65–69	90 (24.39%)	1.302 (1.259 – 1.345)		78 (25.74%)	1.267 (1.235 – 1.299)
70–74	29 (7.86%)	1.291 (1.239 – 1.344)		29 (9.57%)	1.241 (1.201 – 1.282)
75–79	13 (3.52%)	1.291 (1.229 – 1.353)		10 (3.30%)	1.233 (1.180 – 1.285)
80–84	5 (1.36%)	1.341 (1.253 – 1.429)		1 (0.33%)	1.309 (1.152 – 1.465)
Race/Ethnicity	N= 364		0.62	N= 297		0.16	0.86
Non-Hispanic White	294 (80.77%)	1.310 (1.270 – 1.349)		255 (85.86%)	1.294 (1.260 – 1.328)
African American/Black	42 (11.54%)	1.308 (1.261 – 1.356)		16 (5.39%)	1.247 (1.197 – 1.298)
BMI (kg/m2)	N= 369		<0.001*	N= 303		<0.001*	0.008*
<18.5	1 (0.27%)	1.351 (1.173 – 1.528)		3 (0.99%)	1.280 (1.185 – 1.376)
18.5–24.9	74 (20.05%)	1.389 (1.361 – 1.417)		113 (37.29%)	1.310 (1.274 – 1.345)
25–29.9	206 (55.83%)	1.349 (1.329 – 1.370)		104 (34.32%)	1.281 (1.246 – 1.317)
30–34.9	76 (20.60%)	1.299 (1.273 – 1.326)		72 (23.76%)	1.240 (1.203 – 1.276)
35–37.0	12 (3.25%)	1.159 (1.106 – 1.212)		11 (3.63%)	1.236 (1.180 – 1.293)
History of fragility fracture at baseline	N= 360		0.077	N= 295		0.43	0.53
No	341 (94.72%)	1.312 (1.271 – 1.353)		260 (88.14%)	1.272 (1.234 – 1.310)
Yes	19 (5.28%)	1.273 (1.215 – 1.331)		35 (11.86%)	1.260 (1.213 – 1.307)
Diabetes	N= 365		0.008*	N= 299		0.82	0.099
No	322 (88.22%)	1.318 (1.276 – 1.360)		280 (93.65%)	1.260 (1.223 – 1.298)
Yes	43 (11.78%)	1.278 (1.231 – 1.324)		19 (6.35%)	1.256 (1.206 – 1.306)
Multivitamin use	N= 342		0.80	N= 292		0.77	0.63
No	177 (51.75%)	1.310 (1.266 – 1.354)		177 (60.62%)	1.269 (1.229 – 1.309)
Yes	165 (48.25%)	1.308 (1.265 – 1.350)		115 (39.38%)	1.272 (1.230 – 1.314)
Caffeine use	N= 343		0.30	N= 291		0.93	0.26
Never	31 (9.04%)	1.289 (1.240 – 1.338)		23 (7.90%)	1.277 (1.225 – 1.329)
>0- ⩽1 servings/day	103 (30.03%)	1.316 (1.272 – 1.360)		58 (19.93%)	1.273 (1.229 – 1.317)
>1- ⩽2.5 servings/day	109 (31.78%)	1.316 (1.270 – 1.362)		99 (34.02%)	1.265 (1.221 – 1.308)
>2.5- ⩽3.5 servings/day	58 (16.91%)	1.334 (1.284 – 1.384)		84 (28.87%)	1.268 (1.223 – 1.314)
>3.5 servings/day	42 (12.24%)	1.322 (1.270 – 1.374)		27 (9.28%)	1.261 (1.213 – 1.309)
Smoking status	N= 366		0.74	N= 302		0.092	0.12
Never	181 (49.45%)	1.310 (1.268 – 1.353)		161 (53.31%)	1.278 (1.240 – 1.316)
Past	161 (43.99%)	1.305 (1.262 – 1.348)		123 (40.73%)	1.266 (1.226 – 1.306)
Current	24 (6.56%)	1.319 (1.264 – 1.375)		18 (5.96%)	1.237 (1.186 – 1.289)
Alcohol use	N= 343		0.018*	N= 291		0.24	0.28
Never / Rarely	62 (18.08%)	1.293 (1.249 – 1.337)		56 (19.24%)	1.252 (1.207 – 1.297)
1–3/ month	13 (3.79%)	1.336 (1.272 – 1.399)		30 (10.31%)	1.261 (1.213 – 1.308)
1/ week	34 (9.91%)	1.306 (1.255 – 1.357)		43 (14.78%)	1.281 (1.236 – 1.326)
2–4/ week	64 (18.66%)	1.320 (1.273 – 1.367)		51 (17.53%)	1.269 (1.225 – 1.313)
5–6/ week	40 (11.66%)	1.340 (1.290 – 1.390)		31 (10.65%)	1.268 (1.217 – 1.318)
1 / day	53 (15.45%)	1.333 (1.285 – 1.382)		40 (13.75%)	1.279 (1.230 – 1.328)
2–3/ day	61 (17.78%)	1.314 (1.267 – 1.362)		36 (12.37%)	1.301 (1.252 – 1.351)
4–5/ day	11 (3.21%)	1.285 (1.218 – 1.353)		3 (1.03%)	1.245 (1.126 – 1.363)
6+ /day	5 (1.46%)	1.210 (1.122 – 1.299)		1 (0.34%)	1.223 (1.062 – 1.385)
Total MET- hrs/week categories	N= 368		0.10	N= 301		0.35	0.54
1st tertile (0– 13.71)	113 (30.71%)	1.301 (1.259 – 1.343)		110 (36.54%)	1.265 (1.226 – 1.304)
2nd tertile (13.72– 32.48)	129 (35.05%)	1.308 (1.265 – 1.352)		94 (31.23%)	1.281 (1.240 – 1.322)
3rd tertile (⩾32.49)	126 (34.24%)	1.326 (1.282 – 1.369)		97 (32.23%)	1.277 (1.236 – 1.319)
SSRI use	N= 362		0.013*	N= 300		0.80	0.025*
No	339 (93.65%)	1.310 (1.269 – 1.351)		270 (90.00%)	1.271 (1.233 – 1.309)
Yes	23 (6.35%)	1.260 (1.204 – 1.316)		30 (10.00%)	1.267 (1.218 – 1.316)
Falls in the past year	N= 345		0.49	N= 293		0.20
None	293 (84.93%)	1.311 (1.268 – 1.353)		226 (77.13%)	1.267 (1.228 – 1.307)
One fall	42 (12.17%)	1.287 (1.238 – 1.337)		50 (17.06%)	1.265 (1.219 – 1.310)
Two falls	6 (1.74%)	1.306 (1.222 – 1.390)		9 (3.07%)	1.324 (1.260 – 1.389)
Three falls	4 (1.16%)	1.290 (1.191 – 1.389)		8 (2.73%)	1.259 (1.191 – 1.328)