Table 4.

SIRs for PTSD and incident fractures, stratified by gender, age at first PTSD diagnosis, depression status, substance abuse/dependence status, somatic comorbidity status, and follow-up time.

	Any fracture SIR (95% CI)	Neck SIR (95% CI)	Spine and pelvis SIR (95% CI)	Shoulder and humerus SIR (95% CI)	Forearm SIR (95% CI)	Hand and wrist SIR (95% CI)	Femur SIR (95% CI)
Gender
Female	1.6 (1.4, 1.8)	-	2.4 (1.7, 3.4)	1.4 (0.96, 2.0)	1.3 (1.0, 1.6)	1.5 (1.2, 1.9)	1.6 (1.1, 2.3)
Male	1.9 (1.6, 2.3)	3.4 (1.1, 7.8)	1.4 (0.68, 2.6)	1.8 (1.0, 3.0)	1.7 (1.2, 2.3)	1.8 (1.4, 2.2)	1.5 (0.8, 2.6)
Age at first PTSD diagnosis(years)
16-39	1.8 (1.5, 2.1)	-	2.0 (1.0, 3.4)	2.8 (1.6, 4.4)	1.1 (0.79 ,1.6)	1.7 (1.3, 2.1)	2.4 (0.9, 5.3)
40-59	1.7 (1.5, 2.0)	-	2.3 (1.4, 3.6)	1.4 (0.88, 2.0)	1.7 (1.4, 2.1)	1.5 (1.1, 1.9)	1.2 (0.65 , 2.0)
60+	1.6 (1.2, 2.1)	-	1.8 (0.81, 3.4)	0.8 (0.3, 1.8)	0.7 (0.36 , 1.4)	1.8 (0.84, 3.5)	1.8 (1.2, 2.6)
Depression
Yes	1.8 (1.2, 2.8)	-	-	-	1.2 (0.44 , 2.6)	2.3 (1.0, 4.3)	-
No	1.7 (1.6, 1.9)	2.3 (0.83, 5.0)	2.2 (1.6, 2.9)	1.5 (1.1, 2.1)	1.4 (1.2, 1.7)	1.6 (1.3, 1.9)	1.6 (1.2, 2.2)
Substance abuse/dependence
Yes	2.9 (2.1, 3.9)	-	3.8 (1.2, 8.8)	5.6 (2.8, 10.0)	2.3 (1.2, 3.9)	2.1 (1.2, 3.4)	-
No	1.6 (1.5, 1.8)	2.0 (0.64, 4.6)	2.0 (1.4, 2.7)	1.2 (0.87, 1.7)	1.3 (1.1, 1.6)	1.6 (1.3, 1.8)	1.5 (1.1, 2.1)
CCI score
0	1.7 (1.5, 1.9)	-	1.8 (1.2, 2.6)	1.3 (0.93, 1.9)	1.4 (1.1, 1.7)	1.6 (1.4, 1.9)	1.3 (0.89, 1.9)
1+	2.1 (1.6, 2.6)	-	3.2 (1.7, 5.5)	2.2 (1.2, 3.6)	1.5 (0.92, 2.2)	1.6 (0.97, 2.4)	2.2 (1.3, 3.4)
Follow-up time (years)
1 to <5	1.7 (1.5, 2.0)	-	1.3 (0.64, 2.3)	2.1 (1.4, 3.1)	1.4 (1.1, 1.9)	1.5 (1.2, 1.9)	2.1 (1.4, 3.1)
5 to <10	1.6 (1.4, 2.0)	5.2 (1.7, 12.0)	2.4 (1.4, 3.9)	1.3 (0.74, 2.2)	1.2 (0.88, 1.7)	1.7 (1.3, 2.2)	0.8 (0.34, 1.6)
10+	2.0 (1.6, 2.4)	-	3.0 (1.6, 5.0)	0.9 (0.34, 1.8)	1.5 (1.0, 2.1)	1.8 (1.2, 2.6)	1.9 (1.0, 3.1)

Results not presented when fewer than five incident fracture cases were identified in a stratification subgroup.