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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Pain. 2018 Nov;159(11):2306–2317. doi: 10.1097/j.pain.0000000000001337

Figure 5. Peripheral CGRP induces squint in restrained mice.

Figure 5

Scored images obtained during the restrained MGS experiment (Fig. 3C, D, E, F) were used to measure eyelid fissure. (A) CD1 in dark, (B) CD1 in light, (C) C57BL/6J in dark and (D) C57BL/6J in light. Average of 2 experiments per strain, scored by 1 blinded individual (n=10 per group for CD1 and n=20 per group for C57BL/6J, ± SEM). Two-way repeated measures ANOVA followed by Sidak’s multiple comparison test to compare baseline and treatment conditions, ****P < 0.001. To compare the effect of treatments, the deltas between the scores after treatment from baseline were compared with an unpaired t-test, ΔΔΔP < 0.001, ΔΔΔΔP < 0.0001.