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Three potent P2X7 antagonists abolish ATP‐induced ethidium uptake but not phagocytosis. (A) Pore function detected by ethidium uptake was measured in fresh human peripheral blood mononuclear cells (PBMCs), prelabelled with FITC‐CD14 antibody and incubated with AF27139, A438079, AZ10606120 and KN62 for 10 min. (B) Fresh human PBMCs prelabelled with APC‐CD14 antibody were incubated with YG fluorescent beads and bead uptake into CD14+ cells measured.
