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. 2018 Oct 18;8:15451. doi: 10.1038/s41598-018-33571-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fecal, oral and vaginal bacteria during maturation in NOD mice. ^*Denotes statistical significance, p < 0.05. (A) Fecal bacterial composition at phylum level, and single phyla comparison between 3w, 6w, 8w, 10w and 13w (week-old) NOD mice. (B) Selected single class comparison between NOD mice of different ages. (C) Fecal bacterial composition at class, order, family and genus level between NOD mice at different ages. (D) Oral bacterial composition at phylum level, and selected single phyla comparison between NOD mice at different ages. (E) Vaginal bacterial composition at phylum level, and selected single phyla comparison between NOD mice at different ages.