Fig. 6. Effects of YLT-11 on the proliferation of xenografts in vivo.
a, b Tumor suppression of MDA-MB-468, MDA-MB-231, and MCF-7 tumor xenografts in mice treated with different concentrations of YLT-11. Tumor size and body weight were measured and calculated every 3 days and presented as mean ± SD (n = 5; *p < 0.05; **p < 0.01). c Tumor tissues from MDA-MB-231 xenografts treated with vehicle or YLT-11 were immunohistochemically analyzed with anti-Ki67, cleaved caspase-3, and CDC25C, CDK1, and P21