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. 2018 Oct 18;8:15384. doi: 10.1038/s41598-018-33736-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Upper row: Simple cyst of the proximal humerus treated by curettage and defect-filling using CERAMENT|BONE VOID FILLER. (A,B) Pre- and post-operative x-rays showing decreased cortical thickness as well an isolated chamber in the distal part of the affected bone (arrow), which is not accessed or filled during the operation. (C–E) X-rays taken after 6 weeks, 3 and 6 months showing increasing product resorption and cortical thickening. (F) X-ray taken after 12 months showing normal cortical thickness in the main part of the cyst, and reduced cortical thickness in the non-treated distal chamber as a sign of possible local recurrence. Lower row: Aneurysmal bone cyst of the distal tibia treated by curettage and defect-filling using CERAMENT|BONE VOID FILLER. (G,H) Pre- and post-operative x-rays showing decreased anterior cortical thickness and complete defect filling. (I–L) X-rays taken after 6 weeks and 3, 6, and 12 months showing increasing product resorption and cortical thickening. Note the increasing distance between the growth-plate and the distal aspect of the cyst.