Table 2.
Correlation between SATB-1 and SDF-1 expression and clinicopathological characterics of PDAC patients
Characteristics | N of cases | SATB-1 level | SDF-1 level | ||||
---|---|---|---|---|---|---|---|
H | L | P value | H | L | P valuea | ||
Total cases | 243 | 172 | 71 | 141 | 102 | ||
Sex | |||||||
Male | 142 | 101 | 41 | 0.889 | 80 | 62 | 0.528 |
Female | 101 | 71 | 30 | 61 | 40 | ||
Age | |||||||
< 60 | 104 | 76 | 28 | 0.496 | 61 | 43 | 0.864 |
≥ 60 | 139 | 96 | 43 | 80 | 59 | ||
Differentiation | |||||||
Poor | 68 | 58 | 10 | 0.008** | 46 | 22 | 0.158 |
Moderate | 118 | 78 | 40 | 65 | 53 | ||
Well | 57 | 36 | 21 | 30 | 27 | ||
T stage | |||||||
T1 | 4 | 2 | 2 | 0.003** | 2 | 2 | 0.303 |
T2 | 28 | 15 | 13 | 14 | 14 | ||
T3 | 176 | 122 | 54 | 100 | 76 | ||
T4 | 35 | 32 | 3 | 25 | 10 | ||
TNM stage (AJCC)b | |||||||
I | 17 | 10 | 7 | 0.025* | 10 | 9 | 0.057 |
II | 130 | 88 | 57 | 72 | 58 | ||
III | 62 | 46 | 14 | 32 | 28 | ||
IV | 34 | 28 | 6 | 27 | 7 | ||
Lymph node metastasis | |||||||
Positive | 147 | 119 | 28 | 0.000** | 99 | 48 | 0.000** |
Negative | 96 | 53 | 43 | 42 | 54 |
aChi-square test, *P < 0.05, **P < 0.01
bAmerican Joint Committee on Cancer (AJCC), patients were staged in accordance with the 7th Edition of the AJCC Cancer’s’ TNM Classification; N of cases number of cases, T stage tumor stage; TNM tumor node metastasis, H high, L low