Table 2.
Levels of upregulated and downregulated DEG across all comparisons and over-represented networks across comparisons with sufficient levels of DEG.
| Comparison Group | Upregulated DEG | Downregulated DEG | Enriched Networks |
|---|---|---|---|
| Dairy calves compared over time | |||
| Dairy 48 h versus Dairy 0 h | 140 | 613 | Post-Translational Modification, Small Molecule Biochemistry, Cellular Movement |
| Immunological Disease, Infectious Diseases, Organismal Injury and Abnormalities | |||
| Amino Acid Metabolism, Post-Translational Modification, Small Molecule Biochemistry | |||
| Cell Death and Survival, Cellular Compromise, Inflammatory Response | |||
| Cell Cycle, Cellular Development, Free Radical Scavenging | |||
| Dairy 168 h versus Dairy 72 h | 572 | 1156 | Cell Cycle, Cellular Assembly and Organization, DNA Replication, Recombination, and Repair |
| Cell Cycle, Cellular Assembly and Organization, DNA Replication, Recombination, and Repair | |||
| Cell Signalling, Molecular Transport, Vitamin and Mineral Metabolism | |||
| Cellular Development, Cellular Growth and Proliferation, Endocrine System Disorders | |||
| DNA Replication, Recombination, and Repair, Gene Expression, Cell Cycle | |||
| Beef crossbreed calves compared at each time point | |||
| Beef CL 48 h versus Beef LF 48 h | 539 | 177 | Connective Tissue Disorders, Hereditary Disorder, Organismal Injury and Abnormalities |
| Cell Death and Survival, Neurological Disease, Organismal Injury and Abnormalities | |||
| Infectious Diseases, Cell-To-Cell Signalling and Interaction, Cellular Movement | |||
| Cell Death and Survival, Connective Tissue Disorders, Hereditary Disorder | |||
| Infectious Diseases, Antimicrobial Response, Inflammatory Response | |||
| Beef CL 72 h versus Beef LF 72 h | 2 | 0 | N/A |
| Beef CL 168 h versus Beef LF 168 h | 0 | 0 | N/A |
| Beef LF calves compared over time | |||
| Beef LF 48 h versus Beef LF 0 h | 1240 | 781 | Cell Cycle, Cell Death and Survival, Cellular Assembly and Organization |
| Cell Signalling, Molecular Transport, Vitamin and Mineral Metabolism | |||
| Dermatological Diseases and Conditions, Developmental Disorder, Hereditary Disorder | |||
| Lipid Metabolism, Small Molecule Biochemistry, Vitamin and Mineral Metabolism | |||
| Carbohydrate Metabolism, Small Molecule Biochemistry, Embryonic Development | |||
| Beef LF 168 h versus Beef LF 72 h | 535 | 1362 | Cell-To-Cell Signalling and Interaction, Cell Signalling, Molecular Transport |
| Cardiovascular Disease, Cell-To-Cell Signalling and Interaction, Inflammatory Response | |||
| Carbohydrate Metabolism, Molecular Transport, Small Molecule Biochemistry | |||
| Carbohydrate Metabolism, Endocrine System Disorders, Hereditary Disorder | |||
| Cell-mediated Immune Response, Cellular Development, Cellular Function and Maintenance | |||
| Beef CL calves over time | |||
| Beef CL 48 h versus Beef CL 0 h | 1141 | 954 | Cancer, Connective Tissue Disorders, Developmental Disorder |
| Cell Cycle, Reproductive System Development and Function, Cell Death and Survival | |||
| Cell-To-Cell Signalling and Interaction, Immunological Disease, Inflammatory Disease | |||
| Connective Tissue Development and Function, Connective Tissue Disorders, Nervous System Development and Function | |||
| Cardiovascular System Development and Function, Cell Cycle, Skeletal and Muscular System Development and Function | |||
| Beef CL 168 h versus Beef CL 72 h | 45 | 338 | Post translational modification, Cellular movement |
| Cellular movement, Dermatological diseases, Cell-Cell signalling and interaction | |||
| Cellular movement, Immune cell trafficking | |||
| Developmental disorder, Hereditary disorder, Immunological disease | |||
| Cell-Cell signalling and interaction, Haematological system development | |||