Table 1.

Characteristics of peripheral blood- and bone parameters in non-progressive, stable chronic renal failure with features of CKD-MBD.

Characteristics	Baseline	6 weeks			12 weeks
		Control	CRF	P value	Control	CRF	P value
Urea (mmol/L)	9.83 ± 1.85	12.11 ± 2.22	32.94 ± 5.70	<0.01	11.27 ± 3.06	29.87 ± 7.27	<0.01
Creatinine(μmol/L)	15.13 ± 4.00	16.32 ± 2.83	27.64 ± 5.54	<0.01	19.27 ± 9.49	25.00 ± 11.52	0.02
Calcium (mmol/L)	2.54 ± 0.18	2.51 ± 0.15	2.82 ± 0.19	<0.01	2.42 ± 0.22	2.72 ± 0.28	<0.01
PTH (pg/mL)	ND	ND	ND	ND	140.5 ± 68.7	320.8 ± 202.9	<0.01
HgB (mmol/L)	9.25 ± 0.74	9.28 ± 1.00	7.77 ± 1.09	<0.01	9.54 ± 0.71	8.40 ± 1.03	<0.01
RBC (x1012/L)	10.51 ± 0.54	10.11 ± 1.14	9.69 ± 1.06	0.12	10.61 ± 1.14	10.36 ± 1.00	0.44
Trabecular BV/TV (%)	15.02 ± 2.48	13.38 ± 1.50	17.73 ± 0.81	0.02	11.10 ± 2.16	14.25 ± 2.81	<0.01
SMI	1.83 ± 0.21	1.93 ± 0.08	1.81 ± 0.07	0.06	2.02 ± 0.12	1.89 ± 0.13	0.02
Phosphate (mmol/L)	1.86 ± 0.37	1.50 ± 0.30	1.49 ± 0.30	0.59	1.70 ± 0.53	1.64 ± 0.41	0.80
WBC (x109/L)	9.18 ± 2.28	9.95 ± 2.21	10.65 ± 2.65	0.12	9.15 ± 2.85	10.00 ± 3.71	0.25
Granulocytes (%)	4.42 ± 1.26	7.65 ± 1.96	7.18 ± 1.71	0.46	7.95 ± 1.66	7.33 ± 2.26	0.29
B cells (%)	49.33 ± 3.50	54.98 ± 2.88	55.47 ± 3.25	0.81	54.15 ± 3.16	53.55 ± 2.99	0.59
Monocytes (%)	1.43 ± 0.30	2.64 ± 0.87	2.45 ± 0.93	0.40	2.58 ± 0.89	1.95 ± 0.63	0.01
Macrophages (%)	3.92 ± 0.84	3.42 ± 0.64	2.70 ± 0.59	<0.01	3.58 ± 0.74	3.10 ± 0.58	0.03
CD3+CD4+ T cells (%)	19.85 ± 2.09	10.05 ± 2.04	11.26 ± 1.53	0.03	11.68 ± 2.51	12.92 ± 2.07	0.11
CD3+CD8+ T cells (%)	13.67 ± 1.39	10.08 ± 1.07	11.26 ± 1.53	<0.01	10.90 ± 1.46	11.16 ± 1.39	0.66
PB Sca + Flk + EPC (%)*	0.34 ± 0.13	0.48 ± 0.12	0.43 ± 0.10	0.75	0.44 ± 0.26	0.26 ± 0.05	<0.05
BM Sca + Flk + EPC (%)*	ND	ND	ND	ND	0.29 ± 0.22	0.30 ± 0.12	0.69

^*Percentage in Lineage-negative population.