Fig. 1.

Distribution of interbacterial effector–immunity gene homologs across the phylum Spirochaetes. a The distribution of interbacterial effector and immunity gene homologs in genomes from across a phylogenetic tree of genera within the phylum Spirochaetes. Deferribacteres is shown as the outgroup. BLAST hits are normalized to the number of genomes analyzed for each genus. The genus Borrelia shows a significant deviation from the expected frequency relative to other genera (p < 0.05). b Interbacterial effector and immunity gene homologs in genomes of bacterial endosymbionts and pathogens associated with Ixodidae ticks from the phylum Proteobacteria.