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. 2018 Oct 12;10:35. doi: 10.3389/fnsyn.2018.00035

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Copyright © 2018 Pirone, Alexander, Koenig, Cook-Snyder, Palnati, Wickham, Eden, Shrestha, Reijmers, Biederer, Miczek, Dulla and Jacob.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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APC cKO mice show reduced numbers of PV and somatostatin (SST) immuno-positive interneurons in the mPFC. Immunostaining in the mPFC shows reduced numbers of PV and SST immunostained cells in both the prelimbic and infralimbic sub-regions (n = 3 animals, two slices per mouse for each genotype; *p < 0.05, **p < 0.01, ***p < 0.001).