Table 3.

Median $z$-score values with IQRs for each measured parameter and timepoint, separated by pCR status.

	Baseline median $z$-score (IQR)		Early median $z$-score (IQR)		Midpoint median $z$-score (IQR)
	pCR	Non-pCR	pcR	Non-pCR	pcR	Non-pCR
${\mathrm{HbO}}_2$	1.5 (1.1, 1.8)	1.0 (0.4, 1.9)	1.4 (0.8, 1.7)	0.6 (0.1, 1.1)	0.6 (0.4, 1.1)	0.5 (0.2, 1.3)
HHb	2.2 (1.5, 2.7)	1.9 (1.5, 4.0)	1.5 (1.0, 1.9)	1.7 (1.2, 3.4)	1.2 (0.9, 1.6)	1.4 (0.9, 3.0)
${\mathrm{Hb}}_{\mathrm{T}}$	1.8 (1.5, 2.4)	1.4 (0.8, 2.2)	1.4 (0.8, 1.8)	0.9 (0.5, 1.3)	1.0 (0.7, 1.4)	0.9 (0.5, 1.6)
${\mathrm{S}}_{\mathrm{t}}{\mathrm{O}}_2$	$-0.2$$(-0.8,0.1)$	$-1.8$$(-2.3,-0.8)$	0.4 $(-0.3,0.5)$	$-1.2$$(-1.7,-0.4)$	$-0.4$$(-1.0,0.2)$	$-0.9$$(-1.8,-0.6)$
${\mathrm{H}}_2\mathrm{O}$	2.1 (1.5, 2.8)	1.8 (1.2, 3.1)	1.5 (1.3, 2.3)	1.2 (0.8, 3.2)	0.9 (0.4, 2.0)	1.3 (0.9, 2.3)
Lipid	$-1.8$$(-2.9,-1.4)$	$-1.4$$(-2.5,-0.1)$	$-1.0$$(-1.8,-0.6)$	$-0.9$$(-2.2,-0.1)$	$-0.7$$(-1.1,-0.1)$	$-0.9$$(-1.6,-0.6)$
TOI	3.0 (1.7, 3.8)	2.4 (1.6, 4.1)	1.7 (1.2, 2.4)	1.5 (1.2, 4.0)	1.5 (0.9, 2.0)	1.5 (1.2, 3.2)