Table 2.
The top 10 hot genes of rheumatoid arthritis (RA) from the DisGeNET database
| Gene | Gene name | Score | PMIDs |
|---|---|---|---|
| PTPN22 | Protein tyrosine phosphatase, non‐receptor type 22 | 0·567 | 151 |
| TNF | Tumour necrosis factor | 0·506 | 570 |
| HLA‐DRB1 | Major histocompatibility complex, class II, DR beta 1 | 0·44 | 614 |
| IL‐1β | Interleukin‐1 beta | 0·323 | 155 |
| CRP | C‐reactive protein | 0·315 | 75 |
| CTLA‐4 | Cytotoxic T lymphocyte‐associated protein 4 | 0·299 | 61 |
| PADI4 | Peptidyl arginine deiminase 4 | 0·298 | 90 |
| IL‐6 | Interleukin‐6 | 0·297 | 198 |
| MTHFR | Methylenetetrahydrofolate reductase | 0·287 | 53 |
| IL‐10 | Interleukin‐10 | 0·286 | 95 |
Total number of PubMed identifiers (PMIDs) supporting the association.