Table 1. Cyclotetramerization (K_T), peripheral binding (K_p) equilibrium constants and effective molarity (EM) calculated from the data obtained in different experiments in toluene.

	K a c [M–1]	C d [M]	K T [M–3]	K p [M–1]	EM e [M]
GdC a	5.0 × 105		6.3 × 1024		1.0 × 102
AdU a	2.0 × 103		3.2 × 1011		2.0 × 10–2
AaU a	2.0 × 103		1.0 × 1011		6.3 × 10–3
GdC + aC b	5.0 × 105	1.0 × 10–4	— f	— f	— f
		2.0 × 10–5	8.9 × 1024	1.4 × 104	1.4 × 102
		1.0 × 10–5	8.3 × 1024	1.1 × 104	1.3 × 102
		5.0 × 10–6	2.5 × 1025	1.7 × 104	4.0 × 102
		Dilution g	6.3 × 1024	8.5 × 104	1.0 × 102
AdU + aU b	2.0 × 103	1.1 × 10–4	3.5 × 1011	1.0 × 103	2.2 × 10–2

^aData obtained from concentration-dependent experiments (Fig. 3).

^bData obtained from competition experiments (Fig. 5).

^cReference association constant between complementary nucleosides in toluene.25

^dDinucleoside (GdC or AdU) concentration used in the competition experiment.

^eEffective molarities were calculated as EM = K_T/K_a⁴.

^fNot fitted.

^gFitting of the dilution experiment at a constant [GdC]/[aC] 1 : 1 ratio (see Fig. 8).