Table 1.

Institutional changes affecting changes in the delivery process for pediatric continuous renal replacement therapy

• Equipment change from Prisma to Prismaflex

• Standard prescription changed from CVVHD to CVVHDF

• Standard anticoagulation changed from systemic heparin to regional citrate

• Filter change from mostly AN69 to HF2000 membranes

• Adoption of 24 h in-house dialysis nursing staff

• Introduction of emergency department sepsis protocola

• Establishment of a dedicated Renal ICU physician team

• Institutional CRRT Policies & Procedures manual written

• Creation of an institutional CRRT prospective database

• Creation of a prospective CRRT Quality Improvement Team

CVVHD: continuous venovenous hemodialysis; CVVHDF: continuous venovenous hemodialfiltration

^a Akcan Arikan A, Williams EA, Graf JM, et al. Resuscitation Bundle in Pediatric Shock Decreases Acute Kidney Injury and Improves Outcomes. J Pediatr. Dec 2015;167(6):1301–1305