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. 2018 Oct 19;18:283. doi: 10.1186/s12906-018-2338-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effects of MECN on elevated plus maze (EPM) and light-dark box (LDB) tests. Following 30 min of drugs administration, animals were placed in the EPM to record the time they spent (pED₅₀: 1.81; Hill slope: 3.55) (a) as well as number of transitions (pED₅₀: 1.97; Hill slope: 6.71) (b) in the open arm. In LDB, mice were observed for the time spent (pED₅₀: 1.74; Hill slope: 6.65) (c) and total number of transitions (pED₅₀: 2.33; Hill slope: 1.35) (d) in the open lighted compartment. Data are presented as Mean ± SEM (n = 5). MECN = Methanolic extract of Crataeva nurvala; *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group (one-way ANOVA followed by Dunnett's test)