Table 4.
Effect of MECN on thiopental sodium induced hypnosis
| Treatment | Dose (mg/kg) | Responses | |
|---|---|---|---|
| Onset of sleeping | Sleeping duration | ||
| Control | 0.1 ml/mouse | 9.24 ± 0.25 | 50.20 ± 1.86 |
| Diazepam | 1 | 6.97 ± 0.19*** | 98.40 ± 3.83*** |
| MECN | 50 | 8.87 ± 0.60 | 49.00 ± 4.85 |
| MECN | 100 | 7.92 ± 0.27* | 69.60 ± 3.12* |
| MECN | 200 | 7.18 ± 0.28** | 92.20 ± 2.44*** |
Effect of MECN on thiopental sodium induced hypnosis. Values are presented as the Mean ± SEM (n = 5). MECN = Methanolic extract of Crataeva nurvala; *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group (one-way ANOVA followed by Dunnett’s test)