Fig. 3.

HMOX1 was the target gene of miR-31. a HMOX1 was confirmed as a target gene of miR-31 by the biology predicted website microRNA.org; (b) dual-luciferase reporter assay showed HMOX1 was a target gene of miR-31; (c) Western blot analysis detected that protein levels of HMOX1 were significantly increased after treating miR-31 inhibitor; (d) inhibition of miR-31 could increase protein levels of HMOX1; ^*, p < 0.05, vs. the corresponding control group