Table 3.
Detailed Radiographic and Endoscopic Findings in the Screened MAS Cohort
| Patient | Age (y) | Sex | Type of IPMN | No. of Cysts | Location of Cysts | Largest Cyst Size (mm) | Main Duct Dilation (mm) | Liver Findings | GI Symptoms | GI Lesions: Location, GNAS testing (if +) ( 35 ) | Other Findings | Surgical Histopathology |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 22 | F | Branch duct | >10 | H,B,T | 10 | 15.1- × 11.7-mm adenoma | Gastric hyperplastic polyps: Proximal stomach Gastric heterotopia/metaplasia: Duodenal bulb (R201C) Duodenum Ampulla | ||||
| 2 | 27 | M | Mixed | >10 | H,B,T | 34 | 7 (S) | Acute recurrent pancreatitis | Gastric heterotopia/metaplasia: Duodenum (R201H) | Pancreatic atrophy | IPMN with high-grade dysplasia | |
| 3 | 30 | F | None | 4.8-cm adenoma | ||||||||
| 4 | 47 | F | Branch duct | >10 | H,B,T | 5 | Hamartomas | |||||
| 5 | 15 | M | None | 5.2-cm adenoma | ||||||||
| 6 | 53 | F | Branch duct | 5 | H,B | 3 | Pancreas divisum | |||||
| 7 | 59 | M | Mixed | >10 | H,B,T | 13 | 8 (D) | Fatty liver Hamartomas Small cysts | Acute pancreatitis | |||
| 8 | 16 | M | Branch duct | 3 | H | 12 | Fatty liver | |||||
| 9 | 20 | M | Mixed | 6 | H,B | 30 | 6.5 (S) | Acute recurrent pancreatitis | Fundic gland polyp: Stomach body Gastric heterotopia/metaplasia: Proximal esophagus (R201C) Minor papilla Hamartomatous-type polyp: Major papilla | |||
| 10 | 70 | M | Mixed | >10 | H,B,T | 7 | 9 (D) | <1-cm biliary cyst | Acute pancreatitis | Pancreatic atrophy | ||
| 11 | 49 | F | None | Fatty liver | ||||||||
| 12 | 16 | F | Branch duct | >10 | H,B,T | 13 | ||||||
| 13 | 17 | F | Branch duct | 1 | H | 5 | ||||||
| 14 | 36 | F | Branch duct | 1 | H | 8 | ||||||
| 15 | 19 | M | Branch duct | 8 | H,B,T | 24 | Focal nodular hyperplasia | Acute recurrent pancreatitis | Gastric hyperplastic polyps: Proximal stomach Gastric heterotopia/metaplasia: Proximal esophagus (R201C) Proximal duodenum (R201C) Duodenum (R201C) Ampulla (R201C) | Santorinicele Pancreas divisum | ||
| 16 | 28 | F | Branch duct | 1 | H | 6 | <1-cm biliary cyst | |||||
| 17 | 18 | F | Branch duct | 2 | H | 10 | ||||||
| 18 | 33 | F | Branch duct | 2 | H,B | 12 | <1-cm biliary cyst | |||||
| 19 | 27 | F | None | <1-cm biliary cyst | ||||||||
| 20 | 31 | F | Branch duct | 3 | B | 10 | ||||||
| 21 | 42 | F | Branch duct | 6 | H,B,T | 4 | ||||||
| 22 | 23 | M | None | Fatty liver | ||||||||
| 23 | 55 | M | Mixed | >10 | H,B,T | 22 | 13 (D) | 2 Hemangiomas <1 cm biliary cyst | Acute recurrent pancreatitis | 5.5-cm polyp: GE junction, (R201C) Fundic gland polyps: Stomach Gastric heterotopia/metaplasia: Proximal esophagus Duodenum Ampulla (R201C) Foveolar hyperplasia: Stomach body (R201C) | Pancreatic atrophy | IPMN with low-grade dysplasia Gastric polyp with high-grade dysplasia |
| 24 | 46 | F | Mixed | >10 | H,B,T | 9 | 5 (S) | 1.3-cm hemangioma | Gastric hyperplastic polyp: GE junction (R201H) Gastric heterotopia/metaplasia: Duodenum (R201H) | Pancreatic atrophy | ||
| 25 | 24 | F | Branch duct | 2 | B | 3 | ||||||
| 26 | 58 | F | Mixed | >10 | H,B,T | 11 | ||||||
| 27 | 57 | M | Mixed | >10 | H,B,T | 16 | 6 (D) | Pancreatic atrophy | ||||
| 28 | 24 | M | Branch duct | 7 | B,T | 5 | ||||||
| 29 | 17 | M | Branch duct | 5 | H,B,T | 5 | 2.7-cm adenoma | |||||
| 30 | 50 | M | Mixed | >10 | H,B,T | 27 | 11 (S) | Gastric hyperplastic polyp: Distal esophagus Gastric heterotopia/metaplasia: Proximal esophagus (R201C) Duodenum (R201C) Intestinal metaplasia: GE junction | Pancreatic atrophy |
Boldface indicates subjects with either worrisome or high-risk features on MRCP.
Abbreviations: B, body; D, diffuse, GE, gastroesophageal; H, head; S, segmental; T, tail.