Table 1.

Clinical Characteristics and Metabolic Bone Laboratories of RYGB Study Subjects Over 5 Years

Characteristic	Baseline	2 y	3.5 y	5 y
Demographics
Age, y	51 ± 14
Sex/menopause status
Premenopausal womena	9
Postmenopausal women	8
Men	4
Race/ethnicity
White	15
Black	2
Hispanic	4
Body composition
Weight, kg	121 ± 17	86 ± 14b	88 ± 14b	88 ± 16b
BMI, kg/m2	45 ± 7	32 ± 5b	33 ± 4b	33 ± 6b
Lean mass, kg	59 ± 9	47 ± 9b	47 ± 8b	47 ± 8b
Fat mass, kg	53 ± 11	32 ± 8b	33 ± 9b	35 ± 10b
Bionutrition data
Physical activity, h/wk	17 ± 20	18 ± 14	25 ± 22	26 ± 23
Calcium intake, mg/d	1327 ± 679	1897 ± 1394b	1605 ± 894	1504 ± 855
Vitamin D intake, IU/d	942 ± 1107	1406 ± 1446	2519 ± 2177	2003 ± 3069b
Laboratory data
Calcium, mg/dL	9.4 ± 0.4	9.3 ± 0.4	9.3 ± 0.5	9.2 ± 0.5
25-Hydoxyvitamin D, ng/mL	30 ± 12	30 ± 9	31 ± 11	31 ± 11
PTH, pg/mL	37 ± 24	39 ± 21	53 ± 27b	54 ± 26b,c
Fasting glucose, mg/dL	117 ± 47	94 ± 18b	95 ± 19b	94 ± 19b
Fasting insulin, uIU/mL	22 ± 20	8 ± 7b	6 ± 5b	11 ± 15b
Fasting PYY, ng/mL	110 ± 65	131 ± 53	158 ± 83b	170 ± 106b

Data are presented as mean ± SD or number.

^aNote that two women became menopausal during the course of the 5-y study.

^bDunnett-adjusted P < 0.05 for comparison vs baseline visit.

^c P < 0.05 for comparison of 5-y vs 2-y visit.