Fig. 1. Effects of 24 h pretreatment of HeLa cells with IC20 concentrations of the 1,3,4-thiadiazole–chalcone hybrids 5a, 5c, 5f, and 5m (10 μM for each compound) on ROS generation induced by hydrogen peroxide (10 mM) (A) and endogenous ROS levels (B). The results are presented as the mean ± SD of two independent experiments.
