Fig. 10. Representative agarose gel electrophoresis of plasmid pUC19 treated with 1,3,4-thiadiazole–chalcone hybrid: (A) plasmid pUC19 (12 nM) without (lane P) and with 5a at concentration of 0.05 mM, 0.1 mM, 0.15 mM, 0.2 mM, 0.25 mM, 0.3 mM, and 0.4 mM, lanes 1, 2, 3, 4, 5, 6, and 7, respectively; (B) effects of 5a, 5c, 5f, and 5m on Fe(ii) induced pUC19 damage with compound-iron mole ratios 1 : 1 and 1 : 2.
