Table 1. DPPH scavenging activity of the 1,3,4-thiadiazole–chalcone hybrids 5a–m a .
Compound | IC50 ± SD (μM) |
5a | 12.03 ± 0.50 |
5b | 11.66 ± 0.41 |
5c | 17.17 ± 0.38 |
5d | 11.81 ± 0.31 |
5e | 9.76 ± 0.75 |
5f | 10.33 ± 0.30 |
5g | 17.86 ± 0.03 |
5h | 13.91 ± 0.32 |
5i | 17.82 ± 0.65 |
5j | 18.04 ± 0.23 |
5k | 14.01 ± 0.34 |
5l | 13.45 ± 0.09 |
5m | 11.06 ± 0.24 |
Ascorbic acid | 20.23 ± 0.14 |
aResults are mean values ± SD from three measurements.