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. Author manuscript; available in PMC: 2018 Oct 19.
Published in final edited form as: Neurobiol Aging. 2018 Jul 17;70:265–275. doi: 10.1016/j.neurobiolaging.2018.07.006

Table 4.

Within-subjects general linear model results testing differences in metrics expressed as annualized percent change from baseline among corpus callosum and other tracts (N =39)

Metric Corpus callosum tracts
 F (df) p-value χ2
Splenium, Mean % (SD) Body, Mean % (SD) Genu, Mean % (SD)
AWF −0.57 (1.99)   0.25 (3.05) −0.37 (1.64)   2.59 (1.63a)   0.08   0.06
De,⊥   0.10 (3.89)   0.46 (3.44)   0.99 (2.96)   1.44 (2)   0.25   0.07
FA −0.74 (2.29) −0.60 (3.78) −1.17 (2.94)   1.28 (1.54a)   0.28   0.03
MD   0.01 (3.19)   0.18 (3.26)   0.55 (3.02)   0.77 (1.71a)   0.45   0.02
MK −0.24 (2.94)   0.07 (2.63)   0.14 (1.98)   0.63 (1.72a)   0.63   0.02
Metric Other tracts
 F (df) p-value χ2
Projection, Mean % (SD) Association, Mean % (SD) Limbic, Mean % (SD)
AWF −0.91 (2.48) −0.39 (1.85) −0.53 (3.17)   0.73 (1.71a)   0.46   0.02
De,⊥   1.65 (4.50)   1.66 (2.73)   1.27 (3.37)   0.84 (2)   0.44   0.04
FA −1.93 (2.66) −1.04 (2.21) −0.96 (2.35)   4.14 (1.57a)   0.03   0.10
MD   1.36 (3.58)   1.47 (2.01)   1.07 (2.63)   0.62 (1.57a)   0.50   0.02
MK −0.25 (3.32)   0.12 (2.16)   0.02 (3.64)   0.30 (1.68a)   0.70   0.01

Means across all rows were not significantly different from each other following Bonferroni adjustment for multiple comparisons, except for FA in projection and limbic tracts (p < 0.05).

Key: AWF, axonal water fraction; FA, fractional anisotropy; MD, mean diffusivity; MK, mean kurtosis.

a

Greenhouse-Geissereadjusted degrees of freedom for violating the assumption of sphericity.