Table 3. Mechanisms of expression of overlapping genes.
Translational mechanisms (54 cases: 38 proven and 16 suspected) | Transcriptional mechanisms (17 cases: 16 proven and 1 suspected) | |||
---|---|---|---|---|
Alternative start codona | IRESa | Ribosomal frameshiftingb | Subgenomic RNAsa | Transcriptional slippageb |
29 proven and 16 suspected cases | 2 proven cases | 7 proven cases | 12 proven and 1 suspected cases | 4 proven cases |
aResults in a completely new coding sequence
bResults in the fusion of a new coding sequence downstream of an existing coding sequence