Table 6. Coefficients and 95% confidence intervals from cross-sectional linear regression models of detailed cognitive assessments, 2011:: Regression models of detailed cognitive assessments on APOE genotype and APOE genotype*age.
(1) 1-back D' |
(2) 2-back D' |
(3) Decl. learn, all objects, D' |
(4) Decl. learn, real, D' |
(5) Decl. learn, novel, D' |
(6) ANT: conflict, response time |
(7) ANT: alerting, response time |
(8) ANT: orienting, response time |
|
---|---|---|---|---|---|---|---|---|
Beta (95% CI) | Beta (95% CI) | Beta (95% CI) | Beta (95% CI) | Beta (95% CI) | Beta (95% CI) | Beta (95% CI) | Beta (95% CI) | |
At least one APOE ε4 allele | -0.010 | -0.249 | -0.057 | -0.155 | 0.015 | 3.938 | 5.625 | -5.831 |
(-0.255, 0.236) | (-0.446, -0.053) | (-0.150, 0.036) | (-0.289, -0.020) | (-0.073, 0.102) | (-13.267, 21.144) | (-8.459, 19.710) | (-21.980, 10.317) | |
Age, centered at 65 | -0.041 | -0.044 | -0.018 | -0.029 | -0.009 | -0.391 | 0.131 | 0.627 |
(-0.051, -0.031) | (-0.052, -0.036) | (-0.022, -0.014) | (-0.034, -0.023) | (-0.013, -0.006) | (-1.099, 0.317) | (-0.446, 0.707) | (-0.035, 1.289) | |
At least one APOE ε4 allele * age | -0.010 | 0.000 | -0.003 | 0.007 | -0.009 | -0.826 | -1.141 | -1.250 |
(-0.036, 0.017) | (-0.021, 0.022) | (-0.013, 0.007) | (-0.008, 0.021) | (-0.018, 0.000) | (-2.679, 1.027) | (-2.657, 0.376) | (-2.989, 0.488) | |
N | 787 | 787 | 793 | 793 | 793 | 724 | 725 | 725 |
All models included age, sex, and years of education.