Table 3. Contraceptive progestogens and extra-progestogenic effects (adapted from Regidor and Schindler [14]).
Progestogen | Anti-gonadotrop | Anti-estrogen | Estrogen | Androgen | Anti-androgen | Gluco-corticoid | Anti-mineralo corticoid | Pro Coagulatory | |
---|---|---|---|---|---|---|---|---|---|
Progesterone | + | + | + | − | − | +/− | + | + | − |
Dydrogesterone | + | − | + | − | − | +/− | − | +/− | − |
Medrogestone | + | + | + | − | − | +/− | − | − | |
17a-Hydroxy-Progesterone Derivates | |||||||||
Chlormadinonacetate | + | + | + | − | − | + | + | − | − |
Cyproteronacetate | + | + | + | − | − | ++ | + | − | − |
Megestrolacetate | + | + | + | − | +/− | + | + | − | + |
Medroxyprogesteroneacetate | + | + | + | − | +/− | − | + | − | |
19-Nor-Progesteron-Derivates | |||||||||
Nomegestrolacetate | + | + | + | − | − | +/− | − | − | − |
Promegeston | + | + | + | − | − | − | − | − | − |
Trimegeston | + | + | + | − | − | +/− | − | +/− | − |
19-Nortestosterone-Derivates | |||||||||
Norethisterone | + | + | + | + | + | − | − | − | + |
Lynestrenol | + | + | + | + | + | − | − | − | − |
Norethinodrel | +/− | + | + | + | + | − | − | − | − |
Levonorgestrel | + | + | + | − | + | − | − | − | − |
Norgestimate | + | + | + | − | + | − | − | − | − |
Desogestrel | + | + | + | − | + | − | − | − | − |
Gestoden | + | + | + | − | + | − | + | + | − |
Dienogest | + | + | +/− | +/− | − | + | − | − | − |
Spirolonactone Derivate | |||||||||
Drospirenone | + | + | + | − | − | + | − | + | − |