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. 2018 Oct 2;9(77):34495–34505. doi: 10.18632/oncotarget.26130

Figure 1. TG2 is enriched in MCS cells and required for survival.

Figure 1

(A, B) Meso-1 monolayer cells were harvested and seeded in ultra-low attachment plates for growth as spheroids (MCS cells). (C) TG2 level is markedly enriched in MCS cells and human tumors (T1/T2 = tumors, N1/N2 = control tissue). (D–J) TG2 is required for optimal cell proliferation, spheroid formation, invasion and migration. The values are mean ± SEM and the asterisks indicate a significant change compared to control, n = 3, p < 0.005. The bars = 50 microns in all panels.