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. Author manuscript; available in PMC: 2018 Oct 19.
Published in final edited form as: Environ Sci Technol. 2018 Apr 20;52(9):5469–5478. doi: 10.1021/acs.est.8b00512

Figure 1.

Figure 1.

Screening results of 34 organohalogens using [3H]Ry binding analysis. Compounds in red color represent significant effects toward RyR1 were found at 2 μM at a threshold of p < 0.05 compared with vehicle control using one-way ANOVA followed by Dunnett’s multiple comparisons test. Compounds in green color were those inactive toward RyR1, and they are selected because of their structure properties. Data shown in the figure were conducted from 2 to 3 different preparations with triplicates for each preparation and were normalized to 1% DMSO control (% Veh) and expressed as mean ± SD Table SI1 summarizes the chemical structures tested.