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. 2018 Oct 9;46(5):1147–1159. doi: 10.1042/BST20180169

Figure 1. A summary of the recently reported effects of ascorbate-dependent processes in immune cells.

Figure 1.

(A) Effects on myeloid cells and (B) lymphoid cells. Effects shown in black font represent a reported role of HIF, TET or Jumonji demethylases, text in red indicates a reported effect of HIF, TET or Jumonji in the context of cancer and orange text indicates an effect of ascorbate on immune cells. The inter-relationships between these are indicated by arrows. References from the Figure: Achuthan 2016 [135]; Agathocleous 2017 [53]; Anderson 1980 [164]; Backer 2017 [88] Berger 2013 [101]; Beyaz 2017 [162]; Bhandari 2013 [165]; Bozonet 2015 [108]; Braverman 2016 [86]; Campbell 1999 [166]; Cimmino 2017 [142]; Colegio 2014 [90]; Cramer 2003 [84]; Cribbs 2018 [163]; Cull 2017 [131]; Dang 2011 [112]; De Santa 2009 [137]; Doedens 2010 [93]; [113]; Fluck 2016 [115]; Gaut 2006 [107]; Goldschmidt 1991 [106]; Hammami 2018 [116]; He 2016 [167]; Henke 2016 [94]; Higashiyama 2012 [114]; Huijskens 2014,2015 [122,123]; Ichiyama 2015 [148]; Imtiyaz 2010 [87]; Ishii 2009 [139]; Jeong 2011,2014 [95,96]; Johnston 1991 [168]; Kasahara 2017 [158]; Kim 2012 [169]; Ko 2015 [170]; Kruidenier 2012 [141]; LaMere 2017 [151]; Labiano 2017 [119]; Li 2014 [153]; Li 2018 [83]; Lio 2016 [171]; Liu 2015 [154]; Maeng 2008 [172]; Manning 2013 [124]; Mecklenburgh 2002 [98]; Mingay 2018 [55]; Nair 2016 [156]; Nestor 2016 [147]; Nikolouli 2017 [157]; Noh 2005 [173]; Noman 2014 [92]; Northrup 2017 [161]; Oda 2006 [82]; Orlanski 2016 [174]; Palazon 2017 [117]; Perez-Cruz 2003 [103]; Peyssonnaux 2005 [85]; Ptaschinksi 2015 [146]; Puskas 2002 [175]; Satoh 2010 [134]; Shalova 2015 [89]; Shi 2011 [111]; Shilotri 1977 [176]; Song 2017 [159]; Talks 2000 [177]; Tsagaratou 2017 [160]; Vissers 2004,2007 [178,179]; Vojdani 1993 [180]; Wallner 2016 [132]; Walmsley 2005,2006 [99,100]; Wei 2009 [152]; Yan 2014 [140]; Yildirim 2017 [136]; Yue 2016 [155]; Zhang 2014,2015 [133,145].