Changes (means ± SD) in maximal voluntary isometric contraction torque (MVC; A), range of motion (ROM; B), elbow flexor muscle thickness (C), B-mode ultrasound echo intensity from baseline (D), serum CK activity (E), and muscle soreness by visual analog scale (F) before (pre), immediately after (0), and 1–7 days following the first and second eccentric exercise bouts. A significant (P < 0.05 or P < 0.01) interaction effect is shown for all variables. *Significant difference (P < 0.05) difference between bouts.