LHA central connectivity. The LHA interconnects to all major output systems of the brain (endocrine and autonomic control, behavior, learning, and memory). The relative importance of LHA targets and inputs for feeding and associated behavior is not fully understood and requires systematic and unbiased comparison of LHA connections. Acb, nucleus accumbens; DMH, dorsomedial nucleus of the hypothalamus; DMV, dorsal motor nucleus of vagus; LC, locus coeruleus; NTS, nucleus of the solitary tract; PAG/MLR, periaqueductal gray/mesencephalic locomotor region; PBN, parabrachial nucleus; SNC, substantia nigra pars compacta; Thal, thalamus; VMH, ventromedial hypothalamus.