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. 2018 Oct 19;13:262. doi: 10.1186/s13018-018-0959-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Forest plot of the standardized mean difference of serum COMP in patients with K-L grades 1–4 knee OA compared with controls. A positive standardized mean difference represents a higher serum COMP levels in the knee OA patients compared with controls