Fig. 5.

PA susceptibility of C. albicans cell wall associated mutants. [A] PA sensitivity of C. albicans mutants lacking genes encoding the calcineurin subunits (cna1Δ, and cnb1Δ) was measured relative to the control strains SC5314 and NGY152. * p < 0.05 compared to the controls. Error bars = SEM (n > 3). [B] MIC sensitivity of PA against to strains containing a point mutation in Fks1 or the heterozygous mutant FKS1/fks1Δ was shown as percentage of growth the DMSO control. White bars = 250 µg/ml; grey bars = 500 µg/ml; black bars = 1000 µg/ml PA. Error bars = SEM (n > 3),* p < 0.05 in comparison to 100% growth of each strains, #p < 0.05 in comparison to SC5314. 2way ANOVA test.