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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Pain. 2018 Nov;159(11):2318–2330. doi: 10.1097/j.pain.0000000000001336

Table 6.

Musculoskeletal examination, owner completed metrology instrument, radiographic scoring and nociceptive withdrawal reflex (NWR) data in dogs undergoing the DNIC protocol. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001

Control OA p
Lameness (0-10) 0 (0-0) 3 (3-3) <0.001***
Mobility (0-3) 0 (0-0) 1 (1-2) <0.001***
OA score (0-192) 0 (0-2) 9 (6-12) <0.001***
Joint pain score (0-48) 0 (0-0) 4 (2-5) <0.001***
CBPI pain (0-10) 0 (0-0) 1.125 (0-2.69) 0.0085**
CBPI function (0-10) 0 (0-0) 2.375 (0-6.938) 0.0022**
HCPI (0-44) 1 (0-1.75) 15.5 (3.5-20.5) 0.0026**
ACVS stiffness (0-16) 0 (0-0) 5.5 (0-7) 0.0029**
ACVS function (0-16) 0 (0-0) 4 (0-8.75) 0.0076**
ACVS gait (0-20) 0 (0-0) 5 (2.25-11.5) 0.0022**
ACVS QoL (0-12) 0 (0-0.75) 3 (0-6.25) 0.0076**
LOAD (0-52) 2.5 (0-3) 15.5 (5-25) 0.0042**
SNoRE 13.5 (10.5-18.5) 15.5 (14-25.25) 0.21
Radiographic OA score (0-70) 2 (0.25-3) 20 (16-28) <0.001***
Number of joints radiographically affected 1 (0.25-2) 5 (2-6) <0.001***
NWR threshold 1.9 (95%CI 1.4-2.5) 3.8 (95%CI 2.4-5.2) 0.013*