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Influence of i.t. pretreatment with a GABAA receptor antagonist (SR 95531)on the acute (11-min) antinociceptive effect of HBO2 in the glacial acetic acid-induced abdominal constriction test. Each column represents the percent antinociceptive response ± S.E.M. of at least 10 mice per group. Significance of difference: *, P < 0.05 and ****, P < 0.0001, compared to the saline-pretreated control group.
