Table 1.

Metabolic parameters in 24 obesity hypoventilation syndrome (OHS) subjects before and following adherent CPAP treatment for 2 months, 1 year and 2 years, as well as 12 subjects with OSA who opted not to receive CPAP treatment and were followed for 1 year.

	Adherent				Non-adherent
	Pre-	Post-2 months	Post-12 months	Post-24 months	Pre-	FU-12 months
BMI	43.25 ± 5.27	43.41 ± 5.69	40.79 ± 6.92	42.04 ± 7.14	29.35 ± 1.81	29.72 ± 2.49
Glucose (mg/dl)	104.16 ± 16.13	111.57 ± 33.40	105.38 ± 23.04	101.69 ± 16.59	87.91 ± 11.77	90.75± 8.14
Insulin (μU/mL)	11.64 ± 8.02	7.08 ± 2.75	5.87 ± 2.12*	4.35 ± 2.08*	8.75 ± 2.13	9.78 ± 2.26
Homa-IR	1.56 ± 0.13*	0.94 ± 0.08	0.79 ± 0.05	0.49 ± 0.03	1.13 ± 0.11	1.27 ± 0.13
Adiponectin (μg/ml)	3.49 ± 1.35	4.57 ± 2.36	5.17 ± 2.39*	5.72 ± 2.75*	4.18 ± 1.35	4.20 ± 1.85
RBP4 (μg/ml)	3.17 ± 1.19	2.71 ± 0.81	2.39 ± 0.71*	2.21 ± 0.62*	3.09 ± 0.04	3.14 ± 0.05

^*p<0.01 vs. Pre